Aye it will all come down to the style of play you take, which is only learned by you through game play. Remember that you CAN change secondary late in the game so you're not necessarily "stuck" for all time with your 2nd class.
E/Me is a great combo in part (as mentioned above) because of the added energy storage you get as Ele primary, but it affords you the ability in PvE of dishing out some SERIOUS AoE dmg with your spells, as well has affecting the potency of melee mobs & casters.
R/N could be seriously nasty depending on setup, with posion/disease combo and the ability to hit multi targets later in game with your Ranger skills.....really put a hamper on a mobs attention. Hard to focus on killing opponent when you're trying to make sure YOU'LL live thru the fight..lol
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